Hypothalamus and Pituitary Gland
1. Introduction to the Hypothalamus
1.3. Clinical Correlations
|
Condition |
Lesion Site |
Effect |
|
Diabetes insipidus |
Supraoptic/paraventricular nuclei or posterior pituitary |
ADH deficiency → excessive urination, thirst |
|
Obesity or anorexia |
Ventromedial or lateral nuclei |
Disturbances in feeding regulation |
|
Sleep disorders |
Suprachiasmatic nucleus |
Disrupted circadian rhythm |
|
Thermoregulatory failure |
Anterior or posterior nuclei |
Inability to regulate body temperature |
|
Memory deficits (e.g., Wernicke–Korsakoff) |
Mammillary bodies |
Anterograde amnesia |